VAT included

WHAT IS USED FOR: CMV retinitis in patients with acquired immunodeficiency syndrome (AIDS). Prophylaxis of CMV infection and disease following solid organ transplantation in patients at risk of CMV disease. It contains the active ingredient valganciclovir hydrochloride. Valganciclovir belongs to a group of medicines used to prevent the growth of viruses. It works by acting against a virus called cytomegalovirus or CMV (a type of herpes virus). It prevents this virus from growing and multiplying in the body. In people with poor immunity, CMV can cause infections. Poor immunity can be caused by: HIV/AIDS or by medicines taken after an organ transplant.


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Animal and other laboratory studies have shown Valganciclovir causes infertility, birth defects and cancer. It is possible that these effects may also occur in humans.

When you must not take it

Do not take this medicine if you have an allergy to:

valganciclovir hydrochloride , the active ingredient(s), or to any of the other ingredient(s) listed at the end of this leaflet under Product Description Ganciclovir, valaciclovir or aciclovir or any other similar medicines

If you have very low blood counts for platelets (which help clotting), neutrophils (a type of white blood cell which defends against infection) or low haemoglobin (oxygen carrying substance in the blood).

Some of the symptoms of an allergic reaction may include:

shortness of breath

wheezing or difficulty breathing

swelling of the face, lips, tongue or other parts of the body

rash, itching or hives on the skin

Do not take this medicine after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering. If it has expired or is damaged, return it to your pharmacist for disposal.

If you are not sure whether you should start taking this medicine, talk to your doctor.

Use in children

There is limited information on the safety and effectiveness of the use of Valganciclovir in children. Your doctor will advise you whether Valganciclovir is suitable for your child.

Before you start to take it

Tell your doctor if you have allergies to any other medicines, foods, preservatives or dyes. Especially any medicine which you have taken previously to treat your current condition.

Tell your doctor if you have or have had any of the following medical conditions:

history of low blood counts for platelets (thrombocytopenia), neutrophils (neutropenia) or anaemia

you have or previously have had poor kidney function

Tell your doctor if you are pregnant or plan to become pregnant or are breastfeeding. Valganciclovir Sandoz is not recommended for use during pregnancy. It may affect your developing baby if you take it during pregnancy. Your doctor can discuss with you the risks and benefits involved.

Tell your doctor if you are breast feeding or intend to breast feed. It is not known whether Valganciclovir Sandoz passes into breast milk. Breast feeding is not recommended during treatment with Valganciclovir Sandoz.

You are a woman who could become pregnant and you are not using contraception.

You must use a reliable form of contraception during Valganciclovir therapy, and for at least 30 days after stopping Valganciclovir, unless you are not sexually active. You are a sexually active man.

You should use condoms during and for at least 90 days following treatment with Valganciclovir unless it is certain that your female partner is not at risk of pregnancy.

Information is limited on the safety and effective of Valganciclovir Sandoz in children. Your doctor will advise.

If you have not told your doctor about any of the above, tell him/her before you start taking Valganciclovir Sandoz.

Taking other medicines

Tell your doctor or pharmacist if you are taking any other medicines, including any that you get without a prescription from your pharmacy, supermarket or health food shop.

Valganciclovir Sandoz may interfere with other medicines.

These include:

medicines used to treat gout such as probenecid

medicines used to treat HIV infection, such as zidovudine (AZT) and didanosine(ddI)

a combination of medicines used to treat some infections, such as imipenem/cilastatin

medicine used to prevent organ rejection after a transplant such as mycophenolate mofetil, ciclosporin,

medicines for the treatment of cancer such as vincristine, adriamycin and hydroxyurea

anti-infective medications such as dapsone, pentamidine, flucytosine and amphotericin B

other medications for the treatment of HIV or HIV related infections such as nucleoside analogues

(lamivudine, also known as 3TC; stavudine, also known as D4T; zalcitabine also known as ddc; abacavir; lamivudine / zidovudine or; abacavir / lamivudine /zidovudine combinations).

These medicines may be affected by Valganciclovir Sandoz or may affect how well it works. You may need different amounts of your medicines, or you may need to take different medicines.

Your doctor and pharmacist will have more information on medicines to be careful with or avoid while taking this medicine.

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